Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 6-Chloro-2,4-dimethylpyridazin-3(2H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3(2H)-Pyridazinone, 6-chloro-4-methyl- | HCID 164886 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 6-Chloro-2,4-dimethylpyridazin-3(2H)-one | HCID 59845973 | — |
반응 단계
Methyl iodide (1.3 mL) was added to a mixture of 6-chloro-4-methyl-2H-pyridazin-3-one (2.70 g) and K2CO3 (3.40 g) in N,N-dimethylformamide (27 mL). The resulting mixture was stirred at ambient temperature overnight. Then, water was added and the mixture was extracted with ethyl acetate. The combined organic extracts were washed with water and brine and dried (MgSO4). After removal of the solvent, the title compound was obtained as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846668B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-661409ac12b24b6a80d7ef769018b154 |
| 출처 메모 | uspto-grants-2014_09 |