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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 809524Generated: October 30, 2026

Triphenylphosphine → 5-(2'-amino-1'-methyl-5'-oxo-2-phenyl-1',5'-dihydrospiro[chroman-4,4'-imidazole]-6-yl)-2-fluoro-N-(2-hydroxyethyl)benzamide

https://huagongshe.com/reaction/809524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladium ChlorideHCID 24290—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant(4-Fluoro-3-((2-hydroxyethyl)carbamoyl)phenyl)boronic acidHCID 44717584—
Reactant2'-amino-6-bromo-1'-methyl-2-phenylspiro[chroman-4,4'-imidazol]-5'(1'H)-oneHCID 58423768—
Product5-(2'-amino-1'-methyl-5'-oxo-2-phenyl-1',5'-dihydrospiro[chroman-4,4'-imidazole]-6-yl)-2-fluoro-N-(2-hydroxyethyl)benzamideHCID 67385969—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-175c593fc9bc46ed9ed3670dd2a1cb57
Source noteTest data from https://doi.org/10.1039/C8SC04228D