Sodium ion → 4-(2-Amino-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

HRID 809682Notes

Reaction equation

HRID 809682 reaction equation
[Br:1][c:2]1[c:3]2[n:4]([cH:5][c:6]([CH3:8])[cH:7]1)[n:9][c:10]([NH2:12])[n:11]2.[C:35](=[O:36])([O-:37])[O-:38].[CH3:13][C:14]1([CH3:15])[C:16]([CH3:17])([CH3:18])[O:19][B:20]([C:21]2=[CH:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]2)[O:34]1.[Na+:39].[Na+:40].[O:41]1[CH2:42][CH2:43][O:44][CH2:45][CH2:46]1.[OH2:47]>>[c:2]1([C:21]2=[CH:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]2)[c:3]2[n:4]([cH:5][c:6]([CH3:8])[cH:7]1)[n:9][c:10]([NH2:12])[n:11]2

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 4642098Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylateHCID 214643388-Bromo-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Product 1

HCID 673361314-(2-Amino-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-3d74d23a50d04885be3a37b7d42aae35
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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