2-Methyl-2-butanol → [2-(2,6-Dichloro-benzyl)-5-morpholin-4-yl-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine

HRID 809814Notes

Reaction equation

HRID 809814 reaction equation
[C:40]([OH:41])([CH2:42][CH3:43])([CH3:44])[CH3:45].[CH2:34]1[CH2:35][O:36][CH2:37][CH2:38][NH:39]1.[Cl:1][c:2]1[c:3]([CH2:4][c:5]2[s:6][c:7]3[n:8][c:9]([S:25]([CH3:26])(=[O:27])=[O:28])[n:10][c:11]([NH:14][c:15]4[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]4)[c:12]3[n:13]2)[c:29]([Cl:33])[cH:30][cH:31][cH:32]1>>[Cl:1][c:2]1[c:3]([CH2:4][c:5]2[s:6][c:7]3[n:8][c:9]([N:39]4[CH2:34][CH2:35][O:36][CH2:37][CH2:38]4)[n:10][c:11]([NH:14][c:15]4[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]4)[c:12]3[n:13]2)[c:29]([Cl:33])[cH:30][cH:31][cH:32]1

Participants

4

Reactant 3

HCID 64052-Methyl-2-butanolHCID 8083MorpholineHCID 42641464[2-(2,6-Dichloro-benzyl)-5-methanesulfonyl-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine

Product 1

HCID 42641465[2-(2,6-Dichloro-benzyl)-5-morpholin-4-yl-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine

Sources & evidence

ORD record
ord-3cc73ca329c0476295fc97d9f94100a3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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