(1-(Prop-2-yn-1-yl)piperidin-4-yl)methanol → N-(3-fluoro-4-(2-(3-(4-(hydroxymethyl)piperidin-1-yl)prop-1-ynyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
반응식
[CH2:35]([C:36]#[CH:37])[N:38]1[CH2:39][CH2:40][CH:41]([CH2:44][OH:45])[CH2:42][CH2:43]1.[F:1][c:2]1[cH:3][c:4]([N:19]([C:20](=[O:21])[C:22]2([C:25](=[O:26])[NH2:27])[CH2:23][CH2:24]2)[c:28]2[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([I:18])[s:17]2>>[F:1][c:2]1[cH:3][c:4]([N:19]([C:20](=[O:21])[C:22]2([C:25](=[O:26])[NH2:27])[CH2:23][CH2:24]2)[c:28]2[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([C:37]#[C:36][CH2:35][N:38]1[CH2:39][CH2:40][CH:41]([CH2:44][OH:45])[CH2:42][CH2:43]1)[s:17]2참가 물질
3
반응물 2
생성물 1
출처 및 근거
- ORD 기록
- ord-2cc8da14486b4b35ac2b8ee69f0c3394
- 출처 데이터셋
- Test data from https://doi.org/10.1039/C8SC04228D
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