Acetate → 1-Phenylpiperidin-4-amine

HRID 809938Notes

Reaction equation

HRID 809938 reaction equation
[C:19](#[N:20])[BH3-:21].[CH3:15][C:16](=[O:17])[O-:18].[CH3:24][OH:25].[CH3:26][C:27](=[O:28])[OH:29].[NH4+:14].[Na+:22].[OH2:23].[c:1]1([N:7]2[CH2:8][CH2:9][C:10](=[O:13])[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([N:7]2[CH2:8][CH2:9][CH:10]([NH2:20])[CH2:11][CH2:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

9

Reactant 8

HCID 175AcetateHCID 176Acetic AcidHCID 223AmmoniumHCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 4130091-Phenyl-4-piperidinoneHCID 498716Cyano-borohydride

Product 1

HCID 211933471-Phenylpiperidin-4-amine

Sources & evidence

ORD record
ord-62e43dd7bc5b4d1ab96aa5d93a6d1cf9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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