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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 81008Generated: October 25, 2026

Triethylamine → N-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamine

https://huagongshe.com/reaction/81008

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant4-ChlorobenzylamineHCID 66036—
Reactant2-Bromoethyldiethylammonium bromideHCID 70607—
SolventDichloromethaneHCID 6344—
ProductN-[(4-chlorophenyl)methyl]-N',N'-diethylethane-1,2-diamineHCID 296048—

Reaction Steps

4-Chlorobenzylamine (1.0 mL, 8.2 mmol) was added to a solution of 2-bromo-N,N-diethylethylamine hydrobromide (2.4 g, 9.0 mmol) and triethylamine (3.4 mL, 25 mmol) in dichloromethane (16 mL). The mixture was stirred at room temperature for 5 hours. The mixture was then concentrated to give N1-(4-chlorobenzyl)-N2,N2-diethylethane-1,2-diamine as an oil which was used immediately without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846683B2
Source datasetuspto-grants-2014_09
ORD IDord-ea6cfcefd4a7480d8470f1ed94ea21d7
Source noteuspto-grants-2014_09