Potassium Cation → 5-Hydroxy-7-propargyloxy-2,2-dimethyl-4-chromanone

HRID 810122Notes

Reaction equation

HRID 810122 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH2:9]([C:10]#[CH:11])[Br:12].[CH3:28][C:29]([CH2:30][CH3:31])=[O:32].[I-:8].[K+:5].[K+:6].[K+:7].[OH:13][c:14]1[c:15]2[c:20]([cH:21][c:22]([OH:24])[cH:23]1)[O:19][C:18]([CH3:25])([CH3:26])[CH2:17][C:16]2=[O:27]>>[CH:9]#[C:10][CH2:11][O:24][c:22]1[cH:21][c:20]2[c:15]([c:14]([OH:13])[cH:23]1)[C:16](=[O:27])[CH2:17][C:18]([CH3:25])([CH3:26])[O:19]2

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 6569Methyl Ethyl KetoneHCID 7842Propargyl bromideHCID 19660Carbonate IonHCID 30165Iodide IonHCID 8213625,7-Dihydroxy-2,2-dimethylchroman-4-one

Product 1

HCID 145929635-Hydroxy-7-propargyloxy-2,2-dimethyl-4-chromanone

Sources & evidence

ORD record
ord-f82b447f001640fdba4a9637cb73e25d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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