3-Pyridinemethanamine → 2-[3-[(4-fluorophenyl)methyl]-4-methyl-2-oxoimidazolidin-1-yl]-4-methyl-N-(1,3-thiazol-5-ylmethyl)-1,3-thiazole-5-carboxamide
Reaction equation
[F:16][c:17]1[cH:18][cH:19][c:20]([CH2:21][N:22]2[C:23](=[O:37])[N:24]([c:28]3[s:29][c:30]([C:34](=[O:35])[OH:36])[c:31]([CH3:33])[n:32]3)[CH2:25][CH:26]2[CH3:27])[cH:38][cH:39]1.[F:40][c:41]1[cH:42][cH:43][c:44]([CH2:45][N:46]2[CH:47]([CH3:48])[CH2:49][N:50]([c:51]3[s:52][c:53]([C:54]([OH:55])=[O:56])[c:57]([CH3:58])[n:59]3)[C:60]2=[O:61])[cH:62][cH:63]1.[n:1]1[cH:2][cH:3][cH:4][c:5]([CH2:6][NH2:7])[cH:8]1.[s:9]1[cH:10][n:11][cH:12][c:13]1[CH2:14][NH2:15]>>[s:9]1[cH:10][n:11][cH:12][c:13]1[CH2:14][NH:15][C:34]([c:30]1[s:29][c:28]([N:24]2[C:23](=[O:37])[N:22]([CH2:21][c:20]3[cH:19][cH:18][c:17]([F:16])[cH:39][cH:38]3)[CH:26]([CH3:27])[CH2:25]2)[n:32][c:31]1[CH3:33])=[O:35]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-506dd9ebfeda4be3be60a719518f0c51
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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