Water → 2-Acetyl-4,4-dimethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonyl Chloride

HRID 810376Notes

Reaction equation

HRID 810376 reaction equation
[CH3:1][C:2]1([CH3:15])[CH2:3][N:4]([C:12]([CH3:13])=[O:14])[CH2:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]21.[Cl:16][S:17](=[O:18])(=[O:19])[OH:20].[Cl:22][CH2:23][Cl:24].[OH2:21]>>[CH3:1][C:2]1([CH3:15])[CH2:3][N:4]([C:12]([CH3:13])=[O:14])[CH2:5][c:6]2[cH:7][c:8]([S:17]([Cl:16])(=[O:18])=[O:19])[cH:9][cH:10][c:11]21

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 24638Chlorosulfonic acidHCID 225920161-(4,4-dimethyl-3,4-dihydroisoquinolin-2(1H)-yl)ethanone

Product 1

HCID 225920232-Acetyl-4,4-dimethyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonyl Chloride

Sources & evidence

ORD record
ord-799327aebfdc4deda06df308f9c647cd
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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