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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 810378Generated: October 29, 2026

Aniline → 6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-2-oxo-N-phenylspiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamide

https://huagongshe.com/reaction/810378

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantTrifluoroacetic acidHCID 6422—
ReactantDiphenylphosphinic chlorideHCID 73910—
ReactantDiisopropylethylamineHCID 81531—
Reactantrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acidHCID 66625245—
Product6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-2-oxo-N-phenylspiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamideHCID 75985876—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6cdf947a71b0423faa5f35252e79946b
Source noteTest data from https://doi.org/10.1039/C8SC04228D