4-(4-Chlorophenyl)-1H-pyrrole-2-carboxylic acid → 4-(4-chlorophenyl)-N-(3-methoxy-4-(2-oxo-2-(pyrrolidin-1-yl)ethoxy)phenyl)-1H-pyrrole-2-carboxamide
Reaction equation
[Cl:19][c:20]1[cH:21][cH:22][c:23](-[c:26]2[cH:27][c:28]([C:31](=[O:32])[OH:33])[nH:29][cH:30]2)[cH:24][cH:25]1.[NH2:1][c:2]1[cH:3][c:4]([O:17][CH3:18])[c:5]([O:6][CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:15][cH:16]1>>[NH:1]([c:2]1[cH:3][c:4]([O:17][CH3:18])[c:5]([O:6][CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:15][cH:16]1)[C:31]([c:28]1[cH:27][c:26](-[c:23]2[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]2)[cH:30][nH:29]1)=[O:32]Participants
3
Sources & evidence
- ORD record
- ord-62dbb85c41e94c59bc03864c64a047c7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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