4-(5-(3,5-Dichlorophenyl)-5-(tri fluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid → 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)-2-methylbenzamide

HRID 810927Notes

Reaction equation

HRID 810927 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:24]([F:25])([F:26])[F:27])[CH2:10][C:11]([c:14]3[cH:15][c:16]([CH3:23])[c:17]([C:18](=[O:19])[OH:20])[cH:21][cH:22]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1.[Cl:40][c:41]1[cH:42][c:43]([C:44]2([C:45]([F:46])([F:47])[F:48])[O:49][N:50]=[C:51]([c:52]3[cH:53][cH:54][c:55]([C:56]([NH:57][c:58]4[cH:59][cH:60][c:61]5[c:66]([cH:67]4)[B:64]([OH:65])[O:63][CH2:62]5)=[O:68])[c:69]([CH3:70])[cH:71]3)[CH2:72]2)[cH:73][c:74]([Cl:75])[cH:76]1.[NH2:28][CH2:29][c:30]1[cH:31][cH:32][c:33]2[c:34]([cH:39]1)[B:35]([OH:38])[O:36][CH2:37]2>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:24]([F:25])([F:26])[F:27])[CH2:10][C:11]([c:14]3[cH:15][c:16]([CH3:23])[c:17]([C:18](=[O:19])[NH:28][CH2:29][c:30]4[cH:31][cH:32][c:33]5[c:34]([cH:39]4)[B:35]([OH:38])[O:36][CH2:37]5)[cH:21][cH:22]3)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1

Participants

4

Reactant 3

HCID 231598114-(5-(3,5-Dichlorophenyl)-5-(tri fluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acidHCID 682815336-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-olHCID 866854544-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-methylbenzamide

Product 1

HCID 715758834-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)-2-methylbenzamide

Sources & evidence

ORD record
ord-929a3ae9c7c1430b83454cbc7d16beb6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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