3,5-Dibromo-1-methylpyridin-2(1H)-one → tert-Butyl 3-(6-(5-Bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-3-yloxy)azetidine-1-carboxylate

HRID 810989Notes

Reaction equation

HRID 810989 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([CH:17]3[CH2:18][N:19]([CH2:20][CH3:21])[CH2:22]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[Br:42][c:43]1[c:44](=[O:45])[n:46]([CH3:47])[cH:48][c:49]([Br:50])[cH:51]1.[NH2:23][c:24]1[n:25][cH:26][c:27]([O:30][CH:31]2[CH2:32][N:33]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:34]2)[cH:28][cH:29]1>>[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([O:30][CH:31]3[CH2:32][N:33]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:34]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1

Participants

4

Reactant 3

HCID 36143503,5-Dibromo-1-methylpyridin-2(1H)-oneHCID 58043889Tert-butyl 3-((6-aminopyridin-3-yl)oxy)azetidine-1-carboxylateHCID 580441415-bromo-3-(5-(1-ethylazetidin-3-yl)pyridin-2-ylamino)-1-methylpyridin-2(1H)-one

Product 1

HCID 58043697tert-Butyl 3-(6-(5-Bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-ylamino)pyridin-3-yloxy)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-333d83f0155b4b588cac76cc92ff4d3c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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