Tert-butyl 3-aminoazetidine-1-carboxylate → 3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-azetidine-1-carboxylic acid tert-butyl ester

HRID 811258Notes

Reaction equation

HRID 811258 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH2:24][CH:25]([NH2:27])[CH2:26]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH:11]=[O:12])[cH:13][cH:14][cH:15]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][NH:27][CH:25]3[CH2:24][N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:26]3)[cH:13][cH:14][cH:15]2)[n:7]1

Participants

3

Reactant 2

HCID 1516507Tert-butyl 3-aminoazetidine-1-carboxylateHCID 249019653-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

Product 1

HCID 866032983-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-azetidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-ccbfdc5dd8634aeb9a7569c253bebab1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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