Potassium Cation → 1-[3,5-Bis(trifluoromethyl)phenyl]-2-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methylamino]propan-1-ol

HRID 811317Notes

Reaction equation

HRID 811317 reaction equation
[F:3][C:4]([c:5]1[cH:6][c:7]([CH:15]2[CH:16]([CH3:44])[N:17]([CH2:21][c:22]3[c:23](-[c:32]4[c:33]([O:42][CH3:43])[cH:34][c:35]([F:41])[c:36]([CH:38]([CH3:39])[CH3:40])[cH:37]4)[cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]3)[C:18](=[O:20])[O:19]2)[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:45])[F:46].[K+:2].[OH-:1].[OH2:47]>>[F:3][C:4]([c:5]1[cH:6][c:7]([CH:15]([CH:16]([NH:17][CH2:21][c:22]2[c:23](-[c:32]3[c:33]([O:42][CH3:43])[cH:34][c:35]([F:41])[c:36]([CH:38]([CH3:39])[CH3:40])[cH:37]3)[cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]2)[CH3:44])[OH:19])[cH:8][c:9]([C:11]([F:12])([F:13])[F:14])[cH:10]1)([F:45])[F:46]

Participants

5

Reactant 4

HCID 813Potassium CationHCID 961HydroxideHCID 962WaterHCID 498494512-Oxazolidinone, 5-[3,5-bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-, (4S,5R)-

Product 1

HCID 911158311-[3,5-Bis(trifluoromethyl)phenyl]-2-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methylamino]propan-1-ol

Sources & evidence

ORD record
ord-e6ddbb4c0445414faa3043fb16c9f5ec
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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