1-(Piperidin-4-yl)azepane → N-[1-[4-(azepan-1-yl)piperidin-1-yl]-3-(3,4-diethylphenyl)-1-oxopropan-2-yl]-4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxamide
Reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:11][CH:12]([C:13](=[O:14])[OH:15])[NH:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([N:25]3[C:26](=[O:36])[NH:27][c:28]4[c:29]([cH:32][cH:33][cH:34][cH:35]4)[CH2:30][CH2:31]3)[CH2:23][CH2:24]2)[cH:6][cH:7][c:8]1[CH2:9][CH3:10].[NH:37]1[CH2:38][CH2:39][CH:40]([N:43]2[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]2)[CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:11][CH:12]([C:13](=[O:14])[N:37]2[CH2:38][CH2:39][CH:40]([N:43]3[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]3)[CH2:41][CH2:42]2)[NH:16][C:17](=[O:18])[N:19]2[CH2:20][CH2:21][CH:22]([N:25]3[C:26](=[O:36])[NH:27][c:28]4[c:29]([cH:32][cH:33][cH:34][cH:35]4)[CH2:30][CH2:31]3)[CH2:23][CH2:24]2)[cH:6][cH:7][c:8]1[CH2:9][CH3:10]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d2fdcea04aac4b9f8f855c9d4cef8fe9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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