Dichloromethane → 1-{[5-(4-Methylphenyl)isoxazol-4-yl]carbonyl}-4-phenylpiperidine-4-carbonitrile
Reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:13](=[O:14])[Cl:15])[cH:10][n:11][o:12]2)[cH:6][cH:7]1.[Cl:30][CH2:31][Cl:32].[c:16]1([C:22]2([C:28]#[N:29])[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[cH:17][cH:18][cH:19][cH:20][cH:21]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:13](=[O:14])[N:25]3[CH2:24][CH2:23][C:22]([c:16]4[cH:17][cH:18][cH:19][cH:20][cH:21]4)([C:28]#[N:29])[CH2:27][CH2:26]3)[cH:10][n:11][o:12]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-eec127a0f7324090acdb4d3d0a09f4d3
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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