3-(Pyrrolidin-3-yl)pyridine → 5-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-[3-(3-pyridinyl)-1-pyrrolidinyl]-3-quinolinecarboxylic acid

HRID 811978Notes

Reaction equation

HRID 811978 reaction equation
[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([F:13])[c:11]1[F:12].[NH:22]1[CH2:23][CH:24]([c:27]2[cH:28][n:29][cH:30][cH:31][cH:32]2)[CH2:25][CH2:26]1>>[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([N:22]2[CH2:23][CH:24]([c:27]3[cH:28][n:29][cH:30][cH:31][cH:32]3)[CH2:25][CH2:26]2)[c:11]1[F:12]

Participants

3

Reactant 2

HCID 36136513-(Pyrrolidin-3-yl)pyridineHCID 139109475-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Product 1

HCID 152884415-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-7-[3-(3-pyridinyl)-1-pyrrolidinyl]-3-quinolinecarboxylic acid

Sources & evidence

ORD record
ord-ac18b5e3ed6848fd9f46fb20ccd37f84
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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