3-Amino-3-(2-chlorophenyl)propan-1-ol → 3-([1,1'-biphenyl]-4-ylsulfonyl)-N-[1-(2-chlorophenyl)-3-hydroxypropyl]-1,3-thiazolidine-2-carboxamide

HRID 812018Notes

Reaction equation

HRID 812018 reaction equation
[NH2:24][CH:25]([CH2:26][CH2:27][OH:28])[c:29]1[c:30]([Cl:35])[cH:31][cH:32][cH:33][cH:34]1.[c:1]1(-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH:11]([C:15](=[O:16])[OH:17])[S:12][CH2:13][CH2:14]2)[cH:5][cH:6]1>>[c:1]1(-[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH:11]([C:15](=[O:17])[NH:24][CH:25]([CH2:26][CH2:27][OH:28])[c:29]3[c:30]([Cl:35])[cH:31][cH:32][cH:33][cH:34]3)[S:12][CH2:13][CH2:14]2)[cH:5][cH:6]1

Participants

3

Reactant 2

HCID 170394363-Amino-3-(2-chlorophenyl)propan-1-olHCID 574232213-(Biphenyl-4-ylsulfonyl)-1,3-thiazolidine-2-carboxylic acid

Product 1

HCID 600367783-([1,1'-biphenyl]-4-ylsulfonyl)-N-[1-(2-chlorophenyl)-3-hydroxypropyl]-1,3-thiazolidine-2-carboxamide

Sources & evidence

ORD record
ord-ed6023890011471e8c9dff428c7d2667
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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