Potassium Cation → tert-Butyl 4-ethynylpiperidine-1-carboxylate

HRID 812119Notes

Reaction equation

HRID 812119 reaction equation
[CH3:22][OH:23].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[CH:1](=[O:2])[CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1.[K+:16].[K+:17].[O-:18][C:19]([O-:20])=[O:21].[O:24]=[C:25]([CH3:26])[C:27]([P:28](=[O:29])([O:30][CH3:31])[O:32][CH3:33])=[N+:34]=[N-:35]>>[C:1]([CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1)#[CH:19]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 887MethanolHCID 3283Diethyl EtherHCID 19660Carbonate IonHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylateHCID 136023029(1E)-1-diazo-1-dimethoxyphosphorylpropan-2-one

Product 1

HCID 15550481tert-Butyl 4-ethynylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-e48865277f35491ea6f67c1efaf75e6d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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