Bicarbonate Ion → 2-(Bromomethyl)-1,4-difluorobenzene

HRID 812144Notes

Reaction equation

HRID 812144 reaction equation
[C:15](=[O:16])([OH:17])[O-:18].[Cl:20][CH2:21][Cl:22].[F:1][c:2]1[c:3]([CH2:9][OH:10])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[Na+:19].[P:11]([Br:12])([Br:13])[Br:14]>>[F:1][c:2]1[c:3]([CH2:9][Br:12])[cH:4][c:5]([F:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 24614Phosphorus tribromideHCID 5225992,5-Difluorobenzyl alcohol

Product 1

HCID 5228302-(Bromomethyl)-1,4-difluorobenzene

Sources & evidence

ORD record
ord-836df02a5d1f4487b97855f17aac5621
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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