Sodium ion → 2-[2-(4-Chloro-2-fluorophenyl)ethenyl]-4-[[4-[4-[2-(methylsulfonylmethyl)imidazol-1-yl]butyl]phenoxy]methyl]-1,3-oxazole

HRID 812362Notes

Reaction equation

HRID 812362 reaction equation
[CH3:18][S:19](=[O:20])(=[O:21])[CH2:22][c:23]1[n:24]([CH2:28][CH2:29][CH2:30][CH2:31][c:32]2[cH:33][cH:34][c:35]([OH:38])[cH:36][cH:37]2)[cH:25][cH:26][n:27]1.[Cl:1][c:2]1[cH:3][c:4]([F:17])[c:5]([CH:8]=[CH:9][c:10]2[o:11][cH:12][c:13]([CH2:15][Cl:16])[n:14]2)[cH:6][cH:7]1.[H-:39].[Na+:40]>>[Cl:1][c:2]1[cH:3][c:4]([F:17])[c:5]([CH:8]=[CH:9][c:10]2[o:11][cH:12][c:13]([CH2:15][O:38][c:35]3[cH:34][cH:33][c:32]([CH2:31][CH2:30][CH2:29][CH2:28][n:24]4[c:23]([CH2:22][S:19]([CH3:18])(=[O:20])=[O:21])[n:27][cH:26][cH:25]4)[cH:37][cH:36]3)[n:14]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 166653HydrideHCID 222592974-[4-[2-[(methylsulfonyl)methyl]-1H-imidazol-1-yl]butyl]phenolHCID 691129852-[2-(4-Chloro-2-fluoro-phenyl)-vinyl]-4-chloromethyl-oxazole

Product 1

HCID 695539652-[2-(4-Chloro-2-fluorophenyl)ethenyl]-4-[[4-[4-[2-(methylsulfonylmethyl)imidazol-1-yl]butyl]phenoxy]methyl]-1,3-oxazole

Sources & evidence

ORD record
ord-e4db6159b2ca4fe0aacc48c7b9854426
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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