rac-(4S*,5R*)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole → rac-(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-4-isopropyl-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole
Reaction equation
[CH2:1]([O:2][c:3]1[cH:4][c:5]([CH:6]([CH3:7])[CH3:8])[cH:9][cH:10][c:11]1[C:12]([Cl:13])=[O:14])[CH3:15].[Cl:16][c:17]1[cH:18][cH:19][c:20]([C:23]2([CH3:49])[N:24]=[C:25]([c:36]3[c:37]([O:46][CH2:47][CH3:48])[cH:38][c:39]([C:42]([CH3:43])([CH3:44])[CH3:45])[cH:40][cH:41]3)[NH:26][C:27]2([CH3:28])[c:29]2[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]2)[cH:21][cH:22]1>>[Cl:16][c:17]1[cH:18][cH:19][c:20]([C:23]2([CH3:49])[N:24]=[C:25]([c:36]3[c:37]([O:46][CH2:47][CH3:48])[cH:38][c:39]([CH:42]([CH3:43])[CH3:44])[cH:40][cH:41]3)[NH:26][C:27]2([CH3:28])[c:29]2[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]2)[cH:21][cH:22]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f30a8f97c90b4ce1a593a84dcba78242
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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