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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 812650Generated: October 30, 2026

Hydrochloric Acid → N-((1RS,2SR)-2-(6-fluoropyridin-3-yl)-2-hydroxy-1-((3-(1,1,2,2-tetrafluoroethoxy)phenyl)methyl)ethyl)-4-fluoro-1-naphthalenecarboxamide

https://huagongshe.com/reaction/812650

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Fluoro-1-naphthoic acidHCID 68448—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant(1RS,2SR)-2-amino-1-(6-fluoropyridin-3-yl)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-1-propanolHCID 22261670—
ProductN-((1RS,2SR)-2-(6-fluoropyridin-3-yl)-2-hydroxy-1-((3-(1,1,2,2-tetrafluoroethoxy)phenyl)methyl)ethyl)-4-fluoro-1-naphthalenecarboxamideHCID 22261913—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9f8f65fd413c4b3287a54c984a9c8582
Source noteTest data from https://doi.org/10.1039/C8SC04228D