3-Isocyanato-1lambda6-thiolane-1,1-dione → 1-[1-[2-(6-tert-butyl-4-ethoxy-3-pyridinyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazole-1-carbonyl]piperidin-4-yl]-3-(1,1-dioxothiolan-3-yl)urea
Reaction equation
[N:44](=[C:45]=[O:46])[CH:47]1[CH2:48][S:49](=[O:52])(=[O:53])[CH2:50][CH2:51]1.[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[N:10]2[C:11]([c:31]3[cH:32][n:33][c:34]([C:40]([CH3:41])([CH3:42])[CH3:43])[cH:35][c:36]3[O:37][CH2:38][CH3:39])=[N:12][C:13]([CH3:23])([c:24]3[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]3)[C:14]2([CH3:15])[c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[N:10]2[C:11]([c:31]3[cH:32][n:33][c:34]([C:40]([CH3:41])([CH3:42])[CH3:43])[cH:35][c:36]3[O:37][CH2:38][CH3:39])=[N:12][C:13]([CH3:23])([c:24]3[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]3)[C:14]2([CH3:15])[c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:6][CH2:7]1)[C:45]([NH:44][CH:47]1[CH2:48][S:49](=[O:52])(=[O:53])[CH2:50][CH2:51]1)=[O:46]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-798d1e19363c4ea496ecdaa84f997406
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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