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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 81267Generated: October 27, 2026

(4aR,7aR)-octahydrocyclopenta[b][1,4]oxazine → Hydrochloric Acid

https://huagongshe.com/reaction/81267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4aR,7aR)-octahydrocyclopenta[b][1,4]oxazineHCID 28796216—
ReactantHCID 178461251HCID 178461251—
ProductHydrochloric AcidHCID 313—
ProductHCID 178461234HCID 178461234—

Reaction Steps

Using a procedure analagous to that described in Example 2.1 (Steps 1 and 2) and starting with 4,6-dichloro-3-((trans-4-methylcyclohexyl)methyl)-3H-imidazo[4,5-c]pyridine (Preparative Example 2.3) and (trans)-octahydrocyclopenta[b][1,4]oxazine.HCl (purchased from Enamine), 4,6-dichloro-2-[(trans)-hexahydrocyclopenta[b][1,4]oxazin-4(4aH)-yl]-3-[(trans-4-methylcyclohexyl)methyl]-3H-imidazo[4,5-c]pyridine (racemic) was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846657B2
Source datasetuspto-grants-2014_09
ORD IDord-fb7b30651bc04b418d959cc8f48c0eac
Source noteuspto-grants-2014_09