1-[4-(Trifluoromethyl)-1,3-thiazol-2-yl]piperazine → (2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-thiazol-2-yl)-piperazin-1-yl]-methanone
Reaction equation
[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1.[F:18][C:19]([c:20]1[n:21][c:22]([N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)[s:23][cH:24]1)([F:31])[F:32]>>[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:9])[N:28]2[CH2:27][CH2:26][N:25]([c:22]3[n:21][c:20]([C:19]([F:18])([F:31])[F:32])[cH:24][s:23]3)[CH2:30][CH2:29]2)[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1Participants
3
Sources & evidence
- ORD record
- ord-f667f67a47144a7d9608ffe7a10fa989
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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