4-(Trifluoromethyl)phenylboronic acid → 5-{4-[4-(2,4-Dichloro-phenyl)-2-(4'-trifluoromethyl-biphenyl-4-ylmethyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide

HRID 812856Notes

Reaction equation

HRID 812856 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8](-[c:20]3[cH:21][cH:22][c:23]([N:26]4[CH2:27][C:28](=[O:33])[NH:29][S:30]4(=[O:31])=[O:32])[cH:24][cH:25]3)[cH:9][c:10](-[c:12]3[c:13]([Cl:19])[cH:14][c:15]([Cl:18])[cH:16][cH:17]3)[n:11]2)[cH:34][cH:35]1.[F:36][C:37]([c:38]1[cH:39][cH:40][c:41]([B:44]([OH:45])[OH:46])[cH:42][cH:43]1)([F:47])[F:48]>>[c:2]1(-[c:41]2[cH:40][cH:39][c:38]([C:37]([F:36])([F:47])[F:48])[cH:43][cH:42]2)[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8](-[c:20]3[cH:21][cH:22][c:23]([N:26]4[CH2:27][C:28](=[O:33])[NH:29][S:30]4(=[O:31])=[O:32])[cH:24][cH:25]3)[cH:9][c:10](-[c:12]3[c:13]([Cl:19])[cH:14][c:15]([Cl:18])[cH:16][cH:17]3)[n:11]2)[cH:34][cH:35]1

Participants

3

Reactant 2

HCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 593054905-{4-[2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide

Product 1

HCID 593054855-{4-[4-(2,4-Dichloro-phenyl)-2-(4'-trifluoromethyl-biphenyl-4-ylmethyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide

Sources & evidence

ORD record
ord-e8e8245ba3494fe89110cfa93e705e59
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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