2-(4-Fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxylic acid → N-(3-fluoro-4-(2-(4-(methylcarbamoyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
Reaction equation
[F:29][c:30]1[cH:31][cH:32][c:33](-[n:36]2[n:37][cH:38][cH:39][c:40]([C:43](=[O:44])[OH:45])[c:41]2=[O:42])[cH:34][cH:35]1.[NH2:1][c:2]1[cH:3][c:4]([F:28])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([C:20](=[O:21])[NH:22][CH3:23])[cH:24][cH:25]2)[s:15]3)[cH:26][cH:27]1>>[NH:1]([c:2]1[cH:3][c:4]([F:28])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([C:20](=[O:21])[NH:22][CH3:23])[cH:24][cH:25]2)[s:15]3)[cH:26][cH:27]1)[C:43]([c:40]1[cH:39][cH:38][n:37][n:36](-[c:33]2[cH:32][cH:31][c:30]([F:29])[cH:35][cH:34]2)[c:41]1=[O:42])=[O:44]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e661efe7fb594d4aa4be5b5df231e14e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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