HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 81295Generated: October 30, 2026
Sodium Azide → [4-(4-Azidobutyl)phenyl]acetic acid
https://huagongshe.com/reaction/81295
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | (4-{4-[(Methanesulfonyl)oxy]butyl}phenyl)acetic acid | HCID 71405718 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | [4-(4-Azidobutyl)phenyl]acetic acid | HCID 22566167 | — |
Reaction Steps
Compound 6 (6 g, 0.02 mol) was dissolved in 80 ml of dry DMF then sodium azide (1.8 g, 0.027 mol) was added. The suspension was stirred at 80° C. (oil bath) for 3 h. The solvent was then removed at reduced pressure and the residual oil was treated with CH2Cl2 (100 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08846688B2 |
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| Source dataset | uspto-grants-2014_09 |
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| ORD ID | ord-307f19f4582f4697939f09d30235deab |
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| Source note | uspto-grants-2014_09 |
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