Ethyl 3-methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylate → 4-Methyl-2-(2-oxo-3-(pyridin-2-ylmethyl)imidazolidin-1-yl)thiazole-5-carboxylic acid
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([O:25][CH2:26][CH3:27])=[O:28].[CH3:29][c:30]1[n:31][c:32]([N:40]2[C:41](=[O:52])[N:42]([CH2:45][c:46]3[n:47][cH:48][cH:49][cH:50][cH:51]3)[CH2:43][CH2:44]2)[s:33][c:34]1[C:35](=[O:36])[O:37][CH2:38][CH3:39]>>[CH3:29][c:30]1[n:31][c:32]([N:40]2[C:41](=[O:52])[N:42]([CH2:45][c:46]3[n:47][cH:48][cH:49][cH:50][cH:51]3)[CH2:43][CH2:44]2)[s:33][c:34]1[C:35](=[O:36])[OH:37]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b465eb49393247e5816060ae4635a5d7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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