tert-Butyl piperazine-1-carboxylate → 4-Isoquinolin-7-yl-piperazine-1-carboxylic acid tert-butyl ester

HRID 813231Notes

Reaction equation

HRID 813231 reaction equation
[C:19](=[O:20])([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[cH:1]1[n:2][cH:3][cH:4][c:5]2[cH:6][cH:7][c:8]([O:11][S:12]([C:13]([F:14])([F:15])[F:16])(=[O:17])=[O:18])[cH:9][c:10]12>>[cH:1]1[n:2][cH:3][cH:4][c:5]2[cH:6][cH:7][c:8]([N:29]3[CH2:28][CH2:27][N:26]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:31][CH2:30]3)[cH:9][c:10]12

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 15171928Isoquinolin-7-yl trifluoromethanesulfonate

Product 1

HCID 674009894-Isoquinolin-7-yl-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-678f05215e8b40d79ac4f3be8aa86ac5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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