Potassium Cation → N-tert-butyl-2-{1-[4-(4-chloro-phenyl)-6-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiazole-5-sulfonamide

HRID 813285Notes

Reaction equation

HRID 813285 reaction equation
[C:33]([CH3:34])([CH3:35])([CH3:36])[NH:37][S:38](=[O:39])(=[O:40])[c:41]1[cH:42][n:43][c:44]([Cl:46])[s:45]1.[CH3:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18]([Sn:20]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH2:31][CH3:32])[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1.[F-:47].[K+:48].[OH2:49]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18](-[c:44]4[n:43][cH:42][c:41]([S:38]([NH:37][C:33]([CH3:34])([CH3:35])[CH3:36])(=[O:39])=[O:40])[s:45]4)[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 962WaterHCID 1140TolueneHCID 28179Fluoride IonHCID 434557712-Chloro-thiazole-5-sulfonic acid tert-butylamideHCID 574688274-(4-Chloro-phenyl)-6-methyl-2-(4-tributylstannanyl-imidazol-1-yl)-pyrimidine

Product 1

HCID 57468959N-tert-butyl-2-{1-[4-(4-chloro-phenyl)-6-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-thiazole-5-sulfonamide

Sources & evidence

ORD record
ord-d3794a4d5926445faa1c70688365d362
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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