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HRID81350

反应详情

EQUATION

反应方程式

HRID 81350 的结构方程式

REACTANTS

反应物

1
结构：CO[C@@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1NC(=O)OC(C)(C)C
HCID58522570

rel-Phenylmethyl (3R,4R)-4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-methoxy-1-piperidinecarboxylate

C19H28N2O5

PRODUCTS

生成物

1
结构：CO[C@@H]1CNCC[C@H]1NC(=O)OC(C)(C)C
HCID58522529

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Benzyl (3R,4R)-4-tert-butoxycarbonylamino-3-methoxy-piperidine-1-carboxylate (2.88 g) is dissolved in ethanol and combined with a spatula tip of Pd/C and hydrogenated under H2 pressure (4 bar). After 18 h the catalyst is filtered off and the solvent is eliminated in vacuo. The residue is used in the next reaction step without any further purification.

WORKUP

后处理

  1. filtrationAfter 18 h the catalyst is filtered off
  2. customThe residue is used in the next reaction step without any further purification