tert-Butyl isocyanate → 4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butylamide
Reaction equation
[C:24]([CH3:25])([CH3:26])([CH3:27])[N:28]=[C:29]=[O:30].[CH2:31]([O:32][C:33](=[O:34])[CH2:35][CH2:36][NH:37][C:38]([N:39]1[CH2:40][CH2:41][N:42]([c:43]2[cH:44][cH:45][c:46]([C:47](=[O:48])[NH:49][c:50]3[cH:51][cH:52][c:53]([CH3:54])[c:55]([I:56])[cH:57]3)[cH:58][n:59]2)[CH2:60][CH2:61]1)=[O:62])[CH3:63].[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]>>[I:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[cH:12][n:13][c:14]([N:17]3[CH2:18][CH2:19][N:20]([C:29]([NH:28][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:30])[CH2:21][CH2:22]3)[cH:15][cH:16]2)=[O:23])[cH:5][cH:6][c:7]1[CH3:8]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a03a7e550b444b8e85cb435dde9fcda9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…