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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 813668Generated: October 30, 2026

Bromide ion → 2-(2-Fluoro-4-(trifluoromethyl)phenyl)-1-(methoxycarbonyl)piperidine-4-carboxylic acid

https://huagongshe.com/reaction/813668

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromide ionHCID 259—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantTriethylamineHCID 8471—
Reactanttert-Butyl methyl etherHCID 15413—
ReactantLithium ionHCID 28486—
ReactantDimethyl 2-(2-fluoro-4-(trifluoromethyl)phenyl)piperidine-1,4-dicarboxylateHCID 66735134—
Product2-(2-Fluoro-4-(trifluoromethyl)phenyl)-1-(methoxycarbonyl)piperidine-4-carboxylic acidHCID 66731558—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0c3c7d3b2f9e4618a5183ce3c8f7caff
Source noteTest data from https://doi.org/10.1039/C8SC04228D