4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(6-fluoroquinolin-7-yl)acetamide
Reaction equation
[Br:16][c:17]1[c:18](-[c:23]2[n:24][cH:25][n:26][nH:27]2)[c:19]([NH2:22])[s:20][cH:21]1.[F:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][c:11]1[CH2:12][C:13](=[O:14])[OH:15]>>[F:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][c:11]1[CH2:12][C:13](=[O:15])[NH:22][c:19]1[c:18](-[c:23]2[n:24][cH:25][n:26][nH:27]2)[c:17]([Br:16])[cH:21][s:20]1Participants
3
Sources & evidence
- ORD record
- ord-82998609cbe84201827b4baca41a8f40
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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