Methanol → Methyl 2-chloronicotinate

HRID 813881Notes

Reaction equation

HRID 813881 reaction equation
[CH3:15][OH:16].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][n:10]1.[S:11]([Cl:12])([Cl:13])=[O:14]>>[Cl:1][c:2]1[c:3]([C:4]([O:5][CH3:15])=[O:6])[cH:7][cH:8][cH:9][n:10]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 762582-Chloronicotinic acid

Product 1

HCID 819931Methyl 2-chloronicotinate

Sources & evidence

ORD record
ord-7788052363bd435fa379c41d2476c39b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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