2-(4-Piperidyl)-2-propanol → 2-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol

HRID 813945Notes

Reaction equation

HRID 813945 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1.[NH:20]1[CH2:21][CH2:22][CH:23]([C:26]([CH3:27])([CH3:28])[OH:29])[CH2:24][CH2:25]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1)[N:20]1[CH2:21][CH2:22][CH:23]([C:26]([CH3:27])([CH3:28])[OH:29])[CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 52003212-(4-Piperidyl)-2-propanolHCID 584049784-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholine

Product 1

HCID 584049702-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol

Sources & evidence

ORD record
ord-2f722781ae3042fcaac6f74198bdf0c1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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