4-Phenylbenzoyl chloride → N-{2-[8-(Benzyloxy)-5-chloroquinolin-7-yl]-1-[3-(pyrrolidin-1-ylmethyl)phenyl]ethyl}biphenyl-4-carboxamide
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:20][CH:21]([c:22]2[cH:23][c:24]([CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33]3)[cH:25][cH:26][cH:27]2)[NH2:34])[cH:11][c:12]([Cl:19])[c:13]2[cH:14][cH:15][cH:16][n:17][c:18]12.[c:35]1(-[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:36][cH:37][c:38]([C:41](=[O:42])[Cl:43])[cH:39][cH:40]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:20][CH:21]([c:22]2[cH:23][c:24]([CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33]3)[cH:25][cH:26][cH:27]2)[NH:34][C:41]([c:38]2[cH:37][cH:36][c:35](-[c:44]3[cH:45][cH:46][cH:47][cH:48][cH:49]3)[cH:40][cH:39]2)=[O:42])[cH:11][c:12]([Cl:19])[c:13]2[cH:14][cH:15][cH:16][n:17][c:18]12Participants
3
Sources & evidence
- ORD record
- ord-f6d7a32f72104825a5829bfb19139827
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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