1-(1-Methyl-4-piperidinyl)piperazine → 2-(3,4-diethyl-benzyl)-1-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butan-1,4-dione
Reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)=[O:30])[cH:31][cH:32][c:33]1[CH2:34][CH3:35].[CH3:36][N:37]1[CH2:38][CH2:39][CH:40]([N:43]2[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]2)[CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[N:46]2[CH2:45][CH2:44][N:43]([CH:40]3[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]3)[CH2:48][CH2:47]2)[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)=[O:30])[cH:31][cH:32][c:33]1[CH2:34][CH3:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f5b0763c1e3041b2854ba5722f64e0a3
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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