Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 814133Generated: October 31, 2026

Tetrahydrofuran → N-[5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamide

https://huagongshe.com/reaction/814133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2,4-DichloropyrimidineHCID 77531—
ReactantN-[5-ethynyl-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamideHCID 59511434—
ProductN-[5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamideHCID 59511410—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d6639b14be8b4329a76061f7ab1ff10e
Source noteTest data from https://doi.org/10.1039/C8SC04228D