(2-Methoxy-phenyl)-acetyl isothiocyanate → N-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-(2-methoxyphenyl)acetamide
Reaction equation
[CH3:65][O:66][c:67]1[c:68]([CH2:73][C:74](=[O:75])[N:76]=[C:77]=[S:78])[cH:69][cH:70][cH:71][cH:72]1.[F:1][c:2]1[cH:3][c:4]([NH2:24])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][n:21]([CH3:23])[cH:22]1)[s:17]2.[F:25][c:26]1[cH:27][c:28]([NH:29][C:30]([NH:31][C:32](=[O:33])[CH2:34][c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)=[S:41])[cH:42][cH:43][c:44]1[O:45][c:46]1[cH:47][cH:48][n:49][c:50]2[cH:51][c:52](-[c:53]3[cH:54][cH:55][c:56]([S:57]([CH3:58])(=[O:59])=[O:60])[cH:61][cH:62]3)[s:63][c:64]12>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:77]([NH:76][C:74]([CH2:73][c:68]2[c:67]([O:66][CH3:65])[cH:72][cH:71][cH:70][cH:69]2)=[O:75])=[S:78])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][n:21]([CH3:23])[cH:22]1)[s:17]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-236a9d5f46254f6396ebac2c55a5e873
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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