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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 814410Generated: October 31, 2026

Tetrahydrofuran → 2-[(3,4-Dichloro-5-fluoro-phenyl)-hydroxy-methyl]-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/814410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantMagnesiumHCID 5462224—
Reactant5-Bromo-1,2-dichloro-3-fluorobenzeneHCID 44891199—
Reactant2-Formyl-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 86620860—
Product2-[(3,4-Dichloro-5-fluoro-phenyl)-hydroxy-methyl]-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 66688030—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-743f40679686482a9d947ea536118f95
Source noteTest data from https://doi.org/10.1039/C8SC04228D