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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 814539Generated: October 26, 2026

Hydrochloric Acid → N-[(1RS,2SR)-1-[3-(neopentyloxy)benzyl]-2-(3-chlorophenyl)-2-hydroxyethyl]-4-fluoro-1-naphthamide

https://huagongshe.com/reaction/814539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant4-Fluoro-1-naphthoic acidHCID 68448—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant(1RS,2SR)-2-amino-3-[3-(neopentyloxy)phenyl]-1-(3-chlorophenyl)-1-propanolHCID 22261929—
ProductN-[(1RS,2SR)-1-[3-(neopentyloxy)benzyl]-2-(3-chlorophenyl)-2-hydroxyethyl]-4-fluoro-1-naphthamideHCID 22261678—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d414ba3c32434981b07a305879ae464b
Source noteTest data from https://doi.org/10.1039/C8SC04228D