Methanol → 2-Amino-4-(trifluoromethyl)benzamide

HRID 814606Notes

Reaction equation

HRID 814606 reaction equation
[CH3:17][OH:18].[N+:1]([O-:2])(=[O:3])[c:4]1[c:5]([C:6](=[O:7])[NH2:8])[cH:9][cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]1.[OH-:19].[OH-:21].[Pd+2:20]>>[NH2:1][c:4]1[c:5]([C:6](=[O:7])[NH2:8])[cH:9][cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27757792-Nitro-4-(trifluoromethyl)benzamide

Product 1

HCID 697392-Amino-4-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-1cc30dd5fb5e45139e4cb9fa2c4f736e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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