4-Bromoanisole → 3-(4-Methoxyphenyl)-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol

HRID 814635Notes

Reaction equation

HRID 814635 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH3:10][O:11][c:12]1[cH:13][cH:14][c:15]([N:18]2[CH2:19][CH2:20][N:21]([c:24]3[c:25]([CH3:38])[c:26]([CH3:37])[c:27]4[c:28]([c:35]3[CH3:36])[C:29](=[O:34])[C:30]([CH3:32])([CH3:33])[O:31]4)[CH2:22][CH2:23]2)[cH:16][cH:17]1.[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44]>>[c:2]1([C:29]2([OH:34])[c:28]3[c:27]([c:26]([CH3:37])[c:25]([CH3:38])[c:24]([N:21]4[CH2:20][CH2:19][N:18]([c:15]5[cH:14][cH:13][c:12]([O:11][CH3:10])[cH:17][cH:16]5)[CH2:23][CH2:22]4)[c:35]3[CH3:36])[O:31][C:30]2([CH3:32])[CH3:33])[cH:3][cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 77304-BromoanisoleHCID 8058HexaneHCID 229355955-[4-(4-methoxyphenyl)piperazin-1-yl]-2,2,4,6,7-pentamethyl-1-benzofuran-3(2H)-one

Product 1

HCID 588473523-(4-Methoxyphenyl)-5-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol

Sources & evidence

ORD record
ord-3063c16e4a2b4e60b1a8e00d9e23de5c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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