2-(2,5-Dichloro-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide → 2-{5-Chloro-2-[8-methoxy-3-(2-morpholin-4-yl-ethyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ylamino]-pyrimidin-4-ylamino}-N,N-dimethyl-benzenesulfonamide
Reaction equation
[CH3:22][O:23][c:24]1[c:25]([NH2:43])[cH:26][c:27]2[c:28]([cH:42]1)[CH2:29][CH2:30][N:31]([CH2:34][CH2:35][N:36]1[CH2:37][CH2:38][O:39][CH2:40][CH2:41]1)[CH2:32][CH2:33]2.[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:43][c:25]2[c:24]([O:23][CH3:22])[cH:42][c:28]3[c:27]([cH:26]2)[CH2:33][CH2:32][N:31]([CH2:34][CH2:35][N:36]2[CH2:37][CH2:38][O:39][CH2:40][CH2:41]2)[CH2:30][CH2:29]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-74e34e29747b4353928dfed650a9513f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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