2-(4-Methoxyphenoxy)ethylamine → N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-[(4-methoxyphenyloxy)ethyl]-2,4-pyrimidinediamine

HRID 814751Notes

Reaction equation

HRID 814751 reaction equation
[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([O:28][CH2:29][CH2:30][NH2:31])[cH:26][cH:27]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1>>[c:2]1([NH:31][CH2:30][CH2:29][O:28][c:25]2[cH:24][cH:23][c:22]([O:21][CH3:20])[cH:27][cH:26]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1

Participants

3

Reactant 2

HCID 17977932-(4-Methoxyphenoxy)ethylamineHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

Product 1

HCID 66758450N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-[(4-methoxyphenyloxy)ethyl]-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-1d9b32ac1f5a4030b055a25801537bac
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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